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New preprint from the lab!

We developed a new approach using FLIM to visualize autophagy levels in the mouse brain:

Fluorescence lifetime-based biosensor for monitoring compartmentalized autophagy dynamics in the intact mammalian brain | bioRxiv

Tal Delivers Invited Talk at the Annual Chinese Neuroscience Meeting

New paper from the lab published in Nature Methods

We developed a first of its kind PTEN sensor, which allows to monitor PTEN activity in the living brain for the first time.  

New publication from Huan Ma's lab published in Science!

Tal contributed to this work by helping to measure CREB activity in the mitochondria.
"Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice" was published to Science!
Read more here: https://www.science.org/doi/10.1126/science.adp6547

Tal Receives the Sieratzki Award for Advances in Neuroscience 

Jan 12, 2025

The Sieratzki Award for Advances in Neuroscience is a prestigious accolade established by the Sieratzki family in collaboration with Tel Aviv University.
This annual award recognizes outstanding achievements in neuroscience research, honoring individuals who have made significant contributions to the field.
The award is part of the broader mission of the Sieratzki Institute for Advances in Neuroscience at Tel Aviv University, which aims to promote excellence in brain science through fellowships, state-of-the-art equipment acquisition, and the relaunch of the Sieratzki Prize.


In 2025, five researchers were honored with the Sieratzki Award for their innovative work in neuroscience, including our very own Tal Laviv. The award ceremony took place during the Israel Society For Neuroscience conference in Eilat, Israel in January 2025. 
 

Maya Wins Best Poster Award at ISFN

We are proud to announce that Maya  has been awarded the Best Poster Award at the Israel Society for Neuroscience (ISFN) Conference for her outstanding work on "A Novel Method for Tracking Neuronal Autophagy in the Intact Mouse Brain."
 

Winning the Best Poster Award at ISFN is a prestigious recognition, highlighting both the scientific impact and innovation of a research project. This award is given to researchers whose work demonstrates exceptional novelty, rigorous methodology, and significant contributions to the field of neuroscience.  Maya’s poster showcased a cutting-edge technique for visualizing and tracking autophagic processes in neurons within a living brain, paving the way for deeper insights into neurodegenerative diseases and cellular homeostasis.
 

Her achievement reflects the dedication and excellence of our lab in advancing neuroscience research, and we are thrilled to see her contributions recognized at such a high level. Congratulations, Maya, on this well-deserved honor!

First Preprint From the Lab is Out 

Oct 22, 2024
Tomer developed a new PTEN sensor that allows to monitor PTEN activity in the intact brain. 

Read more here: 
https://www.biorxiv.org/content/10.1101/2024.10.04.616644v1rint

Sharbel Wins Excellent Talk Award 

Oct 22, 2024
Sharbel wins Excellent Talk Award at the 2024 Andi and Larry Wolfe Trainee Workshop in Molecular and Cellular Neuroscience at Weizmann Institute. 

Chen Zuckerberg Initiative- Ben Barres Early Career Acceleration Award

Nov 9, 2023
We are excited that Tal was selected for the Ben Barres Early Career Acceleration Award by the Chen Zuckerberg Initiative (CZI). This award is given to early career investigators to pursue bold ideas with the goal of advancing the biological mechanisms underpinning neurodegenerative disorders.

With this support by CZI, we will use a new approach the lab has developed to monitor autophagy dynamics in vivo at unprecedented scale in order to determine and study early autophagic deficits in neurodegeneration. We hope this work would pave the way to earlier detection and ultimately better therapeutic strategies for neurodegenerative disorders.  

 

To learn more: 

https://chanzuckerberg.com/science/programs-resources/neurodegeneration-challenge/projects/?award=ben-barres-cycle-2

​Tal and Aviv's new publication

Sep 27, 2023

 

Congratulations to Tal and Aviv for their publication in Advanced Materials!
They published the article “Brain-Targeted Liposomes Loaded with MonoclonalAntibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson’s Disease” with the Avi Schroeder Lab.

 

https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202304654

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